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It was developed by the biotechnology firm ICOS and marketed worldwide by Eli Lilly and Company under the brand name Cialis.
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It works by inhibiting an enzyme known as PDE5. A 20 mg dose of Cialis is comparable to a 100 mg dose of sildenafil (Viagra).
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Drug interactions - organic nitrates
Since PDE5 inhibitors such as Cialis may cause transiently low blood pressure (hypotension), organic nitrates should not be taken for at least 48 hours after taking the last dose of Cialis.
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