Update on near deadly clinical trial - explanation for differences in response in animals and humans

[ginpixie]

Snitched from PharmaTimes:
Prior activation of human T-cells could be the reason for the severe adverse reactions triggered by TeGenero's monoclonal antibody TGN1412 in a Phase I trial at London's Northwick Park Hospital last March.

The hypothesis is based on research by a team from Imperial College London, King's College London and the Cambridge-

Comments

[cybogoblin]

And this is why they always need to run human trials. Very interesting to find out what happened there, I even understood a good degree of it :p