In a special episode of House, shot and told predominantly from the perspective of a patient, Mos Def guest-stars as Lee, a man who awakens after a bicycle accident in a small town in New York state, unable to move or communicate in any way apart from blinking his eyes. House, himself injured in a motorcycle mishap, occupies the hospital bed next to Lee and quickly annoys the doctors treating them both by insisting that Lee has "locked-in" syndrome. After House gets Lee transferred to Princeton Plainsboro, the team is on the case to try to "unlock" him. Meanwhile, Wilson suspects House is hiding something when he refuses to divulge why he was in New York and Taub worries that his attempt to quit the team will lead to House cutting him loose.
Episode description from
House Wiki