Here's a idea for a Sue-mocking fic set in the Inu-Yasha universe.
When Naraku tries to create Kanna, something goes horribly
wrong, resulting in him being possed by a Sue. She uses the
shape changing powers of his body get a biologically impossible
figure that would be the envy of any slut!Sue, though no matter
what she does, she still can't get rid of the spider scar
on her back (Wah! Life is so unfair!)
She then uses Naraku's patented Vats-o-Flesh (TM) to create
Bishounen Spawn to do her bidding. Said bidding being to kill
that skanky ho Kagome so she can have Inu-Yahsa all to herself.
In between bungled attempts to assasinate Kagome, she kidnaps
Inu-Yasha (again and again) to win his Twu Lurve, but even her
Sue-powers can't overcome the fact that she still stinks of
Naraku. And every time she kidnaps him, she tries increasingly
bizarre and desperate methods to get the rosary off of his neck
(since that can be the only possible explanation for why
he isn't falling all over her), with each attempt nearly killing
the poor boy.
She probably also tries to kill Kikyo and seduce Sessho-Maru.
Anyone who wants to can use this idea. I might have tried it
myself, but I have no idea what sort of Bishounen Spawn a
Mary Sue would create, or what their powers would be; I just
haven't tortured myself with enough MS fanfics to be able to get
into the mindset.