Here's the basic look:
I change a few things, such the colors of health/mana. It's defaulted to all light-blue. I prefer the colored bars.
The little 3d animations are kinda nifty, and they'll occasionally do random emotes. Additionally, they flinch when injured, and fall over when dead. That's Fubar at the top, and the buttons are all in bongos. Trinket Menu and Autobar are on the right side, just under ShardAce. Itemrack is running along the right side, and can be hidden at the press of a button.
In fact, all those little gray circles at the corners of the UI are buttons.
On the right side, you've got a "Context Menu" on the upper left button, ItemRack on the Upper Right button, and a ItemSync on the lower right. Right-click the lower left button also brings up a calculator.
On the left side, you've got MonkeyQuest on the upper left, though I've replaced Monkey Quest with QuestFu, so the button doesn't do anything. You've got an instant notepad on the upper right button, with multiple pages. And the lower left corner will give you a copy/paste usable copy of your current chatlog window.
Other nifty mods included are things like PingDir, which draws an arrow on the screen indicating the direction of the minimap ping.
Other good news, the base mod,
Mazzle, has an easy to use installer and configuration window. When installing, it recommends that you to delete your entire interface/WTF folders, then put mazzle's in. Personally, I recommend following this advice, installing mazzle on all your characters, then removing mods you don't want, and installing other mods that you do want.
Hereafter, I answer any specific questions about the UI.