Marijuana has been used since 2700 years ago and has been widely used as medicine in the 80′s, but it is now banned as controlled substance. Day by day study start to show that this plant is actually good, it doesn’t cause significant addiction (it is treated the same as alcohol and coffee addiction), and you can’t get overdose from it. The only true bad side effect from this is that it makes you non-ambitious, living in the present and doesn’t worry about the future.
How can it cure cancer? Basically marijuana contain cannabinoid, a compound that is unique and only can be found in marijuana. Strangely, our body contain cannabinoid receptor (CB1 and CB2), that are spread all over our body. When they meet, certain things start to happen. For example, when CB1 in the liver activated it will start lipogenesis (start storing energy), when it meet CB1 in your brain it start to make you hungry and high. When CB2 receptor is activated it will affect the immune system and relieve pain. And some times it will affect your cancer cell, inhibiting their growth or even killing it.
There are lots of cannabinoid substance in marijuana which are delta-9-tetrahydrocannabinol (THC), Tetrahydrocannabinolic Acid (THCA), Tetrahydrocannabivarin(THCV), Cannabidiol (CBD), Cannabichromene (CBC), Cannabigerol(CBG), Cannabinol (CBN). All of them can affect cancer cell in certain way, but THC the dominant substance found, is the most heavily studied.
It has been studied a lot of times and its anti-tumor effect is indisputable. The first human study about how THC affecting brain cancer was released in British Journal of Cancer in 2006 with the result: the brain tumor cell become smaller.
Still not convinced? Are there any other real scientific studies that show marijuana can affect cancer? Apparently there is a ton of them… Go crazy… (Copy and paste the link to your browser)
Marijuana reduce head and neck cancer risk (ncbi.nlm.nih.gov/pubmed/19638490)
Cannabinoid for breast cancer treatment (ncbi.nlm.nih.gov/pubmed/22776349)
THC to induce apoptosis on cancer cell (ncbi.nlm.nih.gov/pubmed/12648025)
CBD inhibit cancer cell invasion (ncbi.nlm.nih.gov/pubmed/19914218)
Cannabinoid make tumor kill themselves (ncbi.nlm.nih.gov/pubmed/15361550)
Cannabinoid doesn’t only inhibit cancer growth or killing it, it do more than that (ncbi.nlm.nih.gov/pubmed/19889794)
Cannaboinoid kill cervical cancer cell (ncbi.nlm.nih.gov/pubmed/19015962)
HU-331, synthesize from CBD can become anticancer drug (ncbi.nlm.nih.gov/pubmed/17237277)
CBD kill leukeumia (ncbi.nlm.nih.gov/pubmed/14692532)
HU-331 as anticancer drug (ncbi.nlm.nih.gov/pubmed/16571653)
Cannabinoid in health and diseases (ncbi.nlm.nih.gov/pubmed/18286801)
Cannabinoid and cancer (ncbi.nlm.nih.gov/pubmed/16250836)
THC and brain tumor (ncbi.nlm.nih.gov/pubmed/17934890)
Met-F-AEA in cannabis inhibit thyroid cancer (ncbi.nlm.nih.gov/pubmed/19189054)
CBD and THC as potential treatment for pain and cancer (ncbi.nlm.nih.gov/pubmed/18354058)
Activated CB1 and CB2 makes colon cancer kill themselves (ncbi.nlm.nih.gov/pubmed/19047095)
The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation. (ncbi.nlm.nih.gov/pubmed/9653194)
Cannabinoids as potential new therapy for the treatment of brain tumor. (ncbi.nlm.nih.gov/pubmed/18088200)
(CBD) induces apoptosis of glioma cells (ncbi.nlm.nih.gov/pubmed/16909207)
Endocannabinoids as emerging suppressors of angiogenesis and tumor invasion(ncbi.nlm.nih.gov/pubmed/17342320)
WIN, a synthetic from cannabinoid can be used in hepatic cancer treatment (ncbi.nlm.nih.gov/pubmed/19059457)
The endocannabinoid system as a target for the development of new drugs for cancer therapy (ncbi.nlm.nih.gov/pubmed/12723496)
Cannabinoid in intestinal cancer (ncbi.nlm.nih.gov/pubmed/19442536)
Anti-tumor activity on cannabinoid on human breast carcinoma (ncbi.nlm.nih.gov/pubmed/16728591)
cannabinoid system as a potential target for pharmacological treatment of Kaposi’s sarcoma (ncbi.nlm.nih.gov/pubmed/19539619)
Cannbinoid derivatives induce cell death on pancreatic cancer cell (ncbi.nlm.nih.gov/pubmed/16500647)
the potential use of cannabinoid agents in cancer immunotherapy (ncbi.nlm.nih.gov/pubmed/19189659)
CBD was able to produce a significant antitumor activity both in vitro and in vivo (ncbi.nlm.nih.gov/pubmed/14617682)
Estrogenic induction of cannabinoid CB1 receptor in human colon cancer cell lines. (ncbi.nlm.nih.gov/pubmed/18938775)
Endocannabinoids and fatty acid amides in cancer (ncbi.nlm.nih.gov/pubmed/11106791)
cannabinoids could be a good palliative agent for cancer patients (ncbi.nlm.nih.gov/pubmed/19394652)
cannabinoids as a new gastric cancer therapy (ncbi.nlm.nih.gov/pubmed/20336665)
Cannabinoids in the treatment of cancer (ncbi.nlm.nih.gov/pubmed/19442435)
onset of execution phase of cannabinoid-induced glioma cell death (ncbi.nlm.nih.gov/pubmed/15451022)
CB2 may be a viable therapeutic target for the treatment of anaplastic thyroid carcinoma (ncbi.nlm.nih.gov/pubmed/18197164)
Cannabis does not increase risk of cancer (ncbi.nlm.nih.gov/pubmed/16835997)
de novo-synthesized ceramide is involved in cannabinoid-induced apoptosis of brain tumor cells (ncbi.nlm.nih.gov/pubmed/11903061)
a new marker of cannabinoid antitumoral activity? (ncbi.nlm.nih.gov/pubmed/17675107)
potential use in the management of malignant gliomas (ncbi.nlm.nih.gov/pubmed/17202146)
cannabinoid administration may be an effective therapeutic strategy for targeting human cancers (ncbi.nlm.nih.gov/pubmed/19425170)
THC activate JunD which then reduce the spread of breast cancer (ncbi.nlm.nih.gov/pubmed/18454173)
Cannabinoid receptors as novel targets for the treatment of melanoma. (ncbi.nlm.nih.gov/pubmed/17065222)
Anti-tumoral action of cannabinoid (ncbi.nlm.nih.gov/pubmed/10700234)
p38 MAPK in CB2 receptor-induced apoptosis of human leukaemia cells (ncbi.nlm.nih.gov/pubmed/16139274)
Delta9-tetrahydrocannabinol and other cannabinoids exert pro-apoptotic actions in tumor cells via the CB2 cannabinoid receptor (ncbi.nlm.nih.gov/pubmed/16624285)
p8 mediates cannabinoid-induced apoptosis of tumor cells (ncbi.nlm.nih.gov/pubmed/16616335)
Control of the cell survival/death decision by cannabinoids (ncbi.nlm.nih.gov/pubmed/11269508)
CB(2) agonists have potential therapeutic interest and deserve to be explored in the management of prostate cancer (ncbi.nlm.nih.gov/pubmed/19690545)
Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors (ncbi.nlm.nih.gov/pubmed/12511587)
cannabinoid therapy for the management of breast cancer (ncbi.nlm.nih.gov/pubmed/16818634)
Cannabinoid and brain tumor (ncbi.nlm.nih.gov/pubmed/17952650)
Cannabinoids induce apoptosis of pancreatic tumor cells via endoplasmic reticulum stress-related genes (ncbi.nlm.nih.gov/pubmed/16818650)
cannabinoids in the treatment of cancer and neurodegenerative diseases (ncbi.nlm.nih.gov/pubmed/16596790)
cannabinoids as potential antitumor agents (ncbi.nlm.nih.gov/pubmed/15638794)
cannabinoids in the management of gliomas (ncbi.nlm.nih.gov/pubmed/15275820)
Cannabinoids protect astroscytes (ncbi.nlm.nih.gov/pubmed/12133838)
Cannabinoid inhibit brain tumor spread (ncbi.nlm.nih.gov/pubmed/18339876)
THC makes brain tumor kill themselves (ncbi.nlm.nih.gov/pubmed/9771884)
THC makes prostate cancer kill themselves (ncbi.nlm.nih.gov/pubmed/10570948)
low doses of cannabinoids may enhance spread of cancer, where as high doses of cannabinoids usually slow or stop cancer cell growth or even kill the cancer cell (ncbi.nlm.nih.gov/pubmed/12182964) - upd: about this one Rick Simpson himself told me that the former claim is false. upd2: but I would read into these texts beginning with this one, before you dare to experiment on yourself or your loved ones. theory before practice, please)
And those are just some of the studies not all, it is estimated that there are over 22,000 studies world wide regarding marijuana as cancer cure.
Breast cancer cells killed by CBD on right compared to untreated breast cancer cells on left. via
thedailybeast.comWhy marijuana is best for brain cancer than others? Because of the blood brain wall, There is no substance that can go into the brain where the brain cancer lies. Meanwhile cannabinoid work by activating receptor that spread in our body, and receptor CB1 is found plenty in the brain.
Was there any living proof that marijuana cure cancer?
In 2011 there is a story of a two year old boy with brain cancer that are secretly being fed with cannabis oil by his father. The boy is cured, however sceptic people say that it was because of the chemo and cannabis only help the boy endure it.
The problem with this alternative treatment is that marijuana is an illegal substance in every country, you won’t be able to “hey, let’s give this a shot.” You might get a bit of marijuana if you try hard, but as study number 60 said small amount of cannabinoid only enhance the spread of cancer. To slow or kill cancer you need a lot of cannabinoid.
There are plenty of people and website that are selling cannabis oil, but be careful as most of them are scam and fake. There is no guarantee that what you buy contain cannabinoid.
(taken from the internets where it's been 404ed)