Withdrawal
Withdrawal from prescription opiates made my joints ache fiercely, and created disappointment that now, not only would I feel the pain, but the euphoria and energy would soon dissipate.
Withdrawl from anti-anxieties is like having the flu without an actual fever. Body tenses from stress and the brains confusion, not knowing how to deal with it without the crutch of a decade's past. It's the mortification of your stomach picking the most inopportune times to light their C4. It's anger over trivial matters and guilt for outbursts when the emotions no longer have any idea how to suppress themselves without their previous assistant.
Withdrawal for a person or place, however related or unrelated, can feel like a prison during a pending apocolypse. A sense of urgency and concern, but an inability to shed what is safe and familiar.