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Fibromyalgia and the Concept of "Central Sensitivity Syndromes"
March's issue of Seminars in Arthritis and Rheumatism (2007 Mar 10) includes an article summarizing the results of recent research conducted by Dr. M.B. Yunus, a prominent fibromyalgia expert and professor of medicine at the University of Illinois College of Medicine at Peoria (Peoria, IL). The format of this research is a critical overview of existing literature combined with the author's own views, aimed at discussing fibromyalgia and overlapping conditions such as irritable bowel syndrome, headaches, and chronic fatigue syndrome, within the concept of "central sensitivity syndromes" (CSS).
According to the researcher, the theory of these conditions belong to a category of central sensitivity syndromes (CSS) is viable, based on associations between the conditions as well as the available evidence for central sensitization (CS) among several of the syndromes. However, he found that such evidence is weak or unavailable for other syndromes that fall into this category, which requires further studies. "The biology of CSS is based on neuroendocrine aberrations, including CS, that interact with psychosocial factors to cause a number of symptoms," the author writes.
"CSS is an important new concept that embraces the biopsychosocial model of disease. Further critical studies are warranted to fully test this concept. However, it seems to have important significance for new directions for research and patient care involving physician and patient education. Each patient, irrespective of diagnosis, should be treated as an individual considering both the biological and psychosocial contributions to his or her symptoms and suffering."
March's issue of Seminars in Arthritis and Rheumatism (2007 Mar 10) includes an article summarizing the results of recent research conducted by Dr. M.B. Yunus, a prominent fibromyalgia expert and professor of medicine at the University of Illinois College of Medicine at Peoria (Peoria, IL). The format of this research is a critical overview of existing literature combined with the author's own views, aimed at discussing fibromyalgia and overlapping conditions such as irritable bowel syndrome, headaches, and chronic fatigue syndrome, within the concept of "central sensitivity syndromes" (CSS).
According to the researcher, the theory of these conditions belong to a category of central sensitivity syndromes (CSS) is viable, based on associations between the conditions as well as the available evidence for central sensitization (CS) among several of the syndromes. However, he found that such evidence is weak or unavailable for other syndromes that fall into this category, which requires further studies. "The biology of CSS is based on neuroendocrine aberrations, including CS, that interact with psychosocial factors to cause a number of symptoms," the author writes.
"CSS is an important new concept that embraces the biopsychosocial model of disease. Further critical studies are warranted to fully test this concept. However, it seems to have important significance for new directions for research and patient care involving physician and patient education. Each patient, irrespective of diagnosis, should be treated as an individual considering both the biological and psychosocial contributions to his or her symptoms and suffering."