4 Drug interactions - organic nitrates In the United States, Cialis has Food and Drug Administration approval and became available in December, 2003 as the third pill after Viagra and Levitra. Due to its 36-hour effect it is also known as the "Weekend Pill".
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Since PDE5 inhibitors such as Cialis may cause transiently low blood pressure (hypotension), organic nitrates should not be taken for at least 48 hours after taking the last dose of Cialis.
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Cialis is a drug used to treat male erectile dysfunction (impotence).
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